I am 47 and peri-menopausal and am experiencing very low mood. I've been taking thyroxine for hypothyroidism since 1998 and wonder if I can take St Johns Wort or if there is something else I can take? I'm feeling more down and low than stressed, and one of the major problems I have is getting up out of bed in the morning. I feel so tired and low it's difficult. My thyroid function has been good and very steady for the last 4-5 years and I've just seen my consultant in July. He's very happy with my thyroid, therefore I'm putting my feelings down to peri-menopause and the symptoms I've been experiencing.

I'm very sorry to read that you are suffering from these challenging symptoms.  

Low mood and extreme fatigue can be classic symptoms of decreasing oestrogen levels. 

We would recommend perhaps taking a course of Salus Haus Epresat multivitamin formula (http://www.salusuk.com/products/epresat.html) to help support energy levels and visiting your GP and requesting a test for iron, in case you are mildly iron deficient (which would exacerbate symptoms of fatigue).

In addition do make sure you are drinking plenty of water (dehydration alone can cause low mood) and eating whole food snacks and meals to maintain blood sugar levels (sudden drops or rises in blood sugar can adversely affect mood) as well as taking a gentle 10 minute walk a day to increase the feel good chemicals, endorphins.

Given your thyroid condition it may also be helpful to see a medical herbalist who would discuss your history and put together suitable complex to support you.

I do hope you find the best course of action to get you back on track and feeling brighter.

With best wishes

Marianna